About Us

The Stomach cancer Pooling (StoP) Project is a consortium of epidemiological studies of gastric cancer.

The project started in July 2012, based on a core group of 10 studies. Several investigators joined the project during the last few years, and the consortium now counts over 30 studies from different world areas.

The main aim of the StoP Project is to examine the role of several lifestyle and genetic determinants in the aetiology of gastric cancer, through pooled analyses of individual-level data, after central collection and validation of the original datasets.

V. 3.2 of the StoP Project harmonized database has been released in year 2020, including 34 studies and a total of 13,121 cases and 31,420 controls.

Publications

The full study design and presentation of the StoP Project have been described in the European Journal of Cancer Prevention:

  • The stomach cancer pooling (StoP) project: study design and presentation. Pelucchi C, Lunet N, Boccia S, Zhang ZF, Praud D, Boffetta P, Levi F, Matsuo K, Ito H, Hu J, Johnson KC, Ferraroni M, Yu GP, Peleteiro B, Malekzadeh R, Derakhshan MH, Ye W, Zaridze D, Maximovitch D, Aragonés N, Martín V, Pakseresht M, Pourfarzi F, Bellavia A, Orsini N, Wolk A, Mu L, Arzani D, Kurtz RC, Lagiou P, Trichopoulos D, Muscat J, La Vecchia C, Negri E. Eur J Cancer Prev 2015 Jan;24(1):16-23. doi: 10.1097/CEJ.0000000000000017. http://www.ncbi.nlm.nih.gov/pubmed/24566154

 

Original articles based on pooled data of the StoP Project:

  • Cigarette smoking and gastric cancer in the Stomach Cancer Pooling (StoP) Project. Praud D, Rota M, Pelucchi C, Bertuccio P, Rosso T, Galeone C, Zhang ZF, Matsuo K, Ito H, Hu J, Johnson KC, Yu GP, Palli D, Ferraroni M, Muscat J, Lunet N, Peleteiro B, Malekzadeh R, Ye W, Song H, Zaridze D, Maximovitch D, Aragonés N, Castaño-Vinyals G, Vioque J, Navarrete-Muñoz EM, Pakseresht M, Pourfarzi F, Wolk A, Orsini N, Bellavia A, Håkansson N, Mu L, Pastorino R, Kurtz RC, Derakhshan MH, Lagiou A, Lagiou P, Boffetta P, Boccia S, Negri E, La Vecchia C. Eur J Cancer Prev. 2018 Mar;27(2):124-133. doi: 10.1097/CEJ.0000000000000290. http://www.ncbi.nlm.nih.gov/pubmed/27560662
  • Alcohol consumption and gastric cancer risk-A pooled analysis within the StoP project consortium. Rota M, Pelucchi C, Bertuccio P, Matsuo K, Zhang ZF, Ito H, Hu J, Johnson KC, Palli D, Ferraroni M, Yu GP, Muscat J, Lunet N, Peleteiro B, Ye W, Song H, Zaridze D, Maximovitch D, Guevara M, Fernández-Villa T, Vioque J, Navarrete-Muñoz EM, Wolk A, Orsini N, Bellavia A, Håkansson N, Mu L, Persiani R, Kurtz RC, Lagiou A, Lagiou P, Galeone C, Bonzi R, Boffetta P, Boccia S, Negri E, La Vecchia C. Int J Cancer. 2017 Nov 15;141(10):1950-1962. doi: 10.1002/ijc.30891. https://www.ncbi.nlm.nih.gov/pubmed/2871891
  • Tobacco smoking and gastric cancer: meta-analyses of published data versus pooled analyses of individual participant data (StoP Project). Ferro A, Morais S, Rota M, Pelucchi C, Bertuccio P, Bonzi R, Galeone C, Zhang ZF, Matsuo K, Ito H, Hu J, Johnson KC, Yu GP, Palli D, Ferraroni M, Muscat J, Malekzadeh R, Ye W, Song H, Zaridze D, Maximovitch D, Aragonés N, Castaño-Vinyals G, Vioque J, Navarrete-Muñoz EM, Pakseresht M, Pourfarzi F, Wolk A, Orsini N, Bellavia A, Håkansson N, Mu L, Pastorino R, Kurtz RC, Derakhshan MH, Lagiou A, Lagiou P, Boffetta P, Boccia S, Negri E, La Vecchia C, Peleteiro B, Lunet N. Eur J Cancer Prev. 2018 May;27(3):197-204. doi: 10.1097/CEJ.0000000000000401.  https://www.ncbi.nlm.nih.gov/pubmed/29595756
  • Alcohol intake and gastric cancer: Meta-analyses of published data versus individual participant data pooled analyses (StoP Project). Ferro A, Morais S, Rota M, Pelucchi C, Bertuccio P, Bonzi R, Galeone C, Zhang ZF, Matsuo K, Ito H, Hu J, Johnson KC, Yu GP, Palli D, Ferraroni M, Muscat J, Malekzadeh R, Ye W, Song H, Zaridze D, Maximovitch D, Fernández de Larrea N, Kogevinas M, Vioque J, Navarrete-Muñoz EM, Pakseresht M, Pourfarzi F, Wolk A, Orsini N, Bellavia A, Håkansson N, Mu L, Pastorino R, Kurtz RC, Derakhshan MH, Lagiou A, Lagiou P, Boffetta P, Boccia S, Negri E, La Vecchia C, Peleteiro B, Lunet N. Cancer Epidemiol. 2018 Jun;54:125-132. doi: 10.1016/j.canep.2018.04.009. https://www.ncbi.nlm.nih.gov/pubmed/29727805
  • Smoking and Helicobacter pylori infection: an individual participant pooled analysis (Stomach Cancer Pooling- StoP Project). Ferro A, Morais S, Pelucchi C, Aragonés N, Kogevinas M, López-Carrillo L, Malekzadeh R, Tsugane S, Hamada GS, Hidaka A, Hernández-Ramírez RU, López-Cervantes M, Zaridze D, Maximovitch D, Pourfarzi F, Zhang ZF, Yu GP, Pakseresht M, Ye W, Plymoth A, Leja M, Gasenko E, Derakhshan MH, Negri E, La Vecchia C, Peleteiro B, Lunet N. Eur J Cancer Prev. 2019 Sep;28:390-396. doi: 10.1097/CEJ.0000000000000471. https://www.ncbi.nlm.nih.gov/pubmed/30272597
  • Citrus fruit intake and gastric cancer: The stomach cancer pooling (StoP) project consortium. Bertuccio P, Alicandro G, Rota M, Pelucchi C, Bonzi R, Galeone C, Bravi F, Johnson KC, Hu J, Palli D, Ferraroni M, López-Carrillo L, Lunet N, Ferro A, Malekzadeh R, Zaridze D, Maximovitch D, Vioque J, Navarrete-Munoz EM, Pakseresht M, Hernández-Ramírez RU, López-Cervantes M, Ward M, Pourfarzi F, Tsugane S, Hidaka A, Zhang ZF, Kurtz RC, Lagiou P, Lagiou A, Boffetta P, Boccia S, Negri E, La Vecchia C. Int J Cancer. 2019 Jun;144:2936-2944. doi: 10.1002/ijc.32046. https://www.ncbi.nlm.nih.gov/pubmed/30521095
  • Sex differences in the prevalence of Helicobacter pylori infection: an individual participant data pooled analysis (StoP Project). Ferro A, Morais S, Pelucchi C, Dierssen-Sotos T, Martín V, López-Carrillo L, Malekzadeh R, Tsugane S, Hamada GS, Hidaka A, Hernández-Ramírez RU, López-Cervantes M, Zaridze D, Maximovitch D, Pourfarzi F, Zhang ZF, Yu GP, Pakseresht M, Ye W, Plymoth A, Leja M, Gasenko E, Derakhshan MH, Negri E, La Vecchia C, Peleteiro B, Lunet N. Eur J Gastroenterol Hepatol. 2019 May;31(5):593-598. doi: 10.1097/MEG.0000000000001389. https://www.ncbi.nlm.nih.gov/pubmed/30839435
  • Education and gastric cancer risk-An individual participant data meta-analysis in the StoP project consortium. Rota M, Alicandro G, Pelucchi C, Bonzi R, Bertuccio P, Hu J, Zhang ZF, Johnson KC, Palli D, Ferraroni M, Yu GP, Galeone C, López-Carrillo L, Muscat J, Lunet N, Ferro A, Ye W, Plymoth A, Malekzadeh R, Zaridze D, Maximovitch D, Kogevinas M, Fernández de Larrea N, Vioque J, Navarrete-Muñoz EM, Tsugane S, Hamada GS, Hidaka A, Pakseresht M, Wolk A, Håkansson N, Hernández-Ramírez RU, López-Cervantes M, Ward M, Pourfarzi F, Mu L, Kurtz RC, Lagiou A, Lagiou P, Boffetta P, Boccia S, Negri E, La Vecchia C. Int J Cancer. 2020 Feb 1;146(3):671-681. doi: 10.1002/ijc.32298. https://www.ncbi.nlm.nih.gov/pubmed/30919464
  • Meat intake and risk of gastric cancer in the Stomach cancer Pooling (StoP) project. Ferro A, Rosato V, Rota M, Costa AR, Morais S, Pelucchi C, Johnson KC, Hu J, Palli D, Ferraroni M, Zhang ZF, Bonzi R, Yu GP, Peleteiro B, López-Carrillo L, Tsugane S, Hamada GS, Hidaka A, Zaridze D, Maximovitch D, Vioque J, Navarrete-Munoz EM, Aragonés N, Martín V, Hernández-Ramírez RU, Bertuccio P, Ward MH, Malekzadeh R, Pourfarzi F, Mu L, Lópes-Cervantes M, Persiani R, Kurtz RC, Lagiou A, Lagiou P, Boffetta P, Boccia S, Negri E, Camargo MC, Curado MP, La Vecchia C, Lunet N. Int J Cancer 2020 Jul 1;147(1):45-55. doi: 10.1002/ijc.32707. https://www.ncbi.nlm.nih.gov/pubmed/31584199
  • Occupational Exposures and Odds of Gastric Cancer: A StoP Project Consortium Pooled Analysis. Shah SC, Boffetta P, Johnson KC, Hu J, Palli D, Ferraroni M, Tsugane S, Hamada GS, Hidaka A, Zaridze D, Maximovich D, Vioque J, Navarrete-Munoz EM, Zhang ZF, Mu L, Boccia S, Pastorino R, Kurtz RC, Rota M, Bonzi R, Negri E, La Vecchia C, Pelucchi C, Hashim D. Int J Epidemiol. 2020 Apr 1;49(2):422-434. doi: 10.1093/ije/dyz263. https://pubmed.ncbi.nlm.nih.gov/31965145
  • Fruits and vegetables intake and gastric cancer risk: A pooled analysis within the Stomach cancer Pooling Project. Ferro A, Costa AR, Morais S, Bertuccio P, Rota M, Pelucchi C, Hu J, Johnson KC, Zhang ZF, Palli D, Ferraroni M, Yu GP, Bonzi R, Peleteiro B, López-Carrillo L, Tsugane S, Hamada GS, Hidaka A, Malekzadeh R, Zaridze D, Maximovich D, Vioque J, Navarrete-Muñoz EM, Alguacil J, Castaño-Vinyals G, Wolk A, Håkansson N, Hernández-Ramírez RU, Pakseresht M, Ward MH, Pourfarzi F, Mu L, López-Cervantes M, Persiani R, Kurtz RC, Lagiou A, Lagiou P, Boffetta P, Boccia S, Negri E, Camargo MC, Curado MP, La Vecchia C, Lunet N. Int J Cancer 2020 Dec 1;147(11):3090-3101. doi: 10.1002/ijc.33134. https://pubmed.ncbi.nlm.nih.gov/32525569/
  • Adult height and risk of gastric cancer: a pooled analysis within the Stomach cancer Pooling Project. Giraldi L, Stojanovic J, Arzani D, Persiani R, Hu J, Johnson KC, Zhang ZF, Ferraroni M, Palli D, Yu GP, La Vecchia C, Pelucchi C, Lunet N, Ferro A, Malekzadeh R, Muscat J, Zaridze D, Maximovich D, Aragones N, Martin V, Vioque J, Navarrete-Munoz EM, Pakseresht M, Negri E, Rota M, Pourfarzi F, Mu L, Kurtz RC, Lagiou A, Lagiou P, Pastorino R, Boccia S. Eur J Cancer Prev. 2020 Sep 10. doi: 10.1097/CEJ.0000000000000613. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/32925512
  • Polyphenol Intake and Gastric Cancer Risk: Findings from the Stomach Cancer Pooling Project (StoP). Vitelli-Storelli F, Rossi M, Pelucchi C, Rota M, Palli D, Ferraroni M, Lunet N, Morais S, López-Carrillo L, Zaridze DG, Maximovich D, Rubín García M, Castaño-Vinyals G, Aragonés N, Garcia de la Hera M, Hernández-Ramírez RU, Negri E, Bonzi R, Ward MH, Lagiou A, Lagiou P, López-Cervantes M, Boffetta P, Camargo MC, Curado MP, Zhang ZF, Vioque J, La Vecchia C, Martín Sánchez V. Cancers (Basel). 2020 Oct 20;12(10):3064. doi: 10.3390/cancers12103064. https://pubmed.ncbi.nlm.nih.gov/33092262
  • Exploring the interactions between Helicobacter pylori (Hp) infection and other risk factors of gastric cancer: A pooled analysis in the Stomach cancer Pooling (StoP) Project. Collatuzzo G, Pelucchi C, Negri E, López-Carrillo L, Tsugane S, Hidaka A, Shigueaki Hamada G, Hernández-Ramírez RU, López-Cervantes M, Malekzadeh R, Pourfarzi F, Mu L, Zhang ZF, Lunet N, La Vecchia C, Boffetta P. Int J Cancer. 2021 Sep 15;149(6):1228-1238. doi: 10.1002/ijc.33678. https://pubmed.ncbi.nlm.nih.gov/33990950/
  • The association between diabetes and gastric cancer: results from the Stomach Cancer Pooling Project Consortium. Dabo B, Pelucchi C, Rota M, Jain H, Bertuccio P, Bonzi R, Palli D, Ferraroni M, Zhang ZF, Sanchez-Anguiano A, Thi-Hai Pham Y, Thi-Du Tran C, Gia Pham A, Yu GP, Nguyen TC, Muscat J, Tsugane S, Hidaka A, Hamada GS, Zaridze D, Maximovitch D, Kogevinas M, Fernàndez de Larrea N, Boccia S, Pastorino R, Kurtz RC, Lagiou A, Lagiou P, Vioque J, Camargo MC, Paula Curado M, Lunet N, Boffetta P, Negri E, La Vecchia C, Luu HN. Eur J Cancer Prev. 2021 Jun 25. doi: 10.1097/CEJ.0000000000000703. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/34183534/
  • Family History and Gastric Cancer Risk: A Pooled Investigation in the Stomach Cancer Pooling (STOP) Project Consortium. Vitelli-Storelli F, Rubín-García M, Pelucchi C, Benavente Y, Bonzi R, Rota M, Palli D, Ferraroni M, Lunet N, Morais S, Ye W, Plymoth A, Malekzadeh R, Tsugane S, Hidaka A, Aragonés N, Castaño-Vinyals G, Zaridze DG, Maximovich D, Vioque J, García-de-la-Hera M, Zhang ZF, Shigueaki Hamada G, Pakseresht M, Pourfarzi F, Mu L, Boccia S, Pastorino R, Yu GP, Lagiou A, Lagiou P, Negri E, La Vecchia C, Martín V. Cancers (Basel). 2021 Jul 30;13(15):3844. doi: 10.3390/cancers13153844. https://pubmed.ncbi.nlm.nih.gov/34359744/
  • Coffee consumption and gastric cancer: a pooled analysis from the Stomach cancer Pooling Project consortium. Martimianaki G, Bertuccio P, Alicandro G, Pelucchi C, Bravi F, Carioli G, Bonzi R, Rabkin CS, Liao LM, Sinha R, Johnson K, Hu J, Palli D, Ferraroni M, Lunet N, Morais S, Tsugane S, Hidaka A, Hamada GS, López-Carrillo L, Hernández-Ramírez RU, Zaridze D, Maximovitch D, Aragonés N, Martin V, Ward MH, Vioque J, Garcia de la Hera M, Zhang ZF, Kurtz RC, Lagiou P, Lagiou A, Trichopoulou A, Karakatsani A, Malekzadeh R, Camargo MC, Curado MP, Boccia S, Boffetta P, Negri E, La Vecchia C. Eur J Cancer Prev. 2021 Sep 17. doi: 10.1097/CEJ.0000000000000680. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/34545022/

Join

The StoP Project is a consortium of epidemiological studies of gastric cancer.
Inclusion criteria for study participation are:

  • case-control study design, including nested case-control and case-cohort derived from cohort studies;
  • inclusion of at least 80 cases of incident, histologically confirmed gastric cancer (including both cardia and non-cardia location).

Investigators interested in joining the consortium, or requiring further information, should write an e-mail to:
stop.project@unimi.it

or contact:

Dr. Eva Negri
Department of Clinical Sciences and Community Health
University of Milan
Via Augusto Vanzetti, 5
Milan – 20133, Italy
e-mail: eva.negri@unimi.it
 
Dr. Claudio Pelucchi
Department of Clinical Sciences and Community Health
University of Milan
Via Augusto Vanzetti, 5
Milan – 20133, Italy
e-mail: claudio.pelucchi@unimi.it

Contacts

For any information regarding the StoP Project consortium, please write an e-mail to:
stop.project@unimi.it